Modulation of cytokine production by 7-hydroxycoumarin in vitro …
网页2010年2月1日 · In this study, we demonstrated that 7HC exhibited cytokine-modulatory activity in influenza virus-infected mice, resulting in the alleviation of influenza infection. 7HC might be useful in understanding the modulation and role of cytokine production in the pathogenesis of influenza infection.
Modulation of cytokine production by 7-hydroxycoumarin in ... - PubMed
网页In this study, we assessed the effects of modulation of cytokine production by 7HC on influenza virus infection in relation to its efficacy in influenza virus-infected mice. 7HC was confirmed to suppress proinflammatory cytokine levels in …
Binding and Molecular Dynamics Studies of 7-Hydroxycoumarin …
网页Coumarin derivatives play a critical role as anticancer, antidiabetic, anticoagulant, and analgesic agents. Here we have studied the cytotoxic activity of 7-hydroxycoumarin derivatives (7HC-1, 7HC-2, and 7HC-3) on mouse macrophage (RAW 264.7) cell lines.
Molecular structure, Normal Coordinate Analysis, harmonic …
网页2013年1月15日 · In this work, we report harmonic vibrational frequencies, molecular structure, NBO and HOMO, LUMO analysis of Umbelliferone also known as 7-hydroxycoumarin (7HC). The optimized geometric bond lengths and bond angles obtained by computation (monomer and dimmer) shows …
7-hydroxycoumarin | Sigma-Aldrich - MilliporeSigma
网页7-Hydroxycoumarin-3-carboxylic acid. Synonym (s): Umbelliferone-3-carboxylic acid. Empirical Formula (Hill Notation): C10H6O5. CAS No.: 779-27-1. Molecular Weight: …
Applicability of coumarin for detecting and measuring hydroxyl …
网页2008年6月24日 · Applicability of coumarin (COU) as fluorescent probe to detect and measure hydroxyl radicals generated by UV irradiation of aqueous suspension of TiO 2 was investigated under aerobic and anaerobic conditions. The fluorescent 7-hydroxycoumarin (7HC) was formed in argon-saturated suspension …
Binding and molecular dynamics studies of 7-hydroxycoumarin
网页2014年4月7日 · Coumarin derivatives play a critical role as anticancer, antidiabetic, anticoagulant, and analgesic agents. Here we have studied the cytotoxic activity of 7-hydroxycoumarin derivatives (7HC-1, 7HC-2, and 7HC-3) on mouse macrophage (RAW 264.7) cell lines.
Computational Studies Followed by Effect of Solvent Polarity and …
网页2022年9月28日 · The UV–visible spectrum of 7HC was obtained and the electronic characteristics HOMO and LUMO energies were monitored by the time-dependent TD-DFT method. The spectral behavior of 7-Hydroxycoumarin was studied using fluorescence spectroscopy in a wide range of polar and non-polar solvents.
Interaction of thyroxine with 7 hydroxycoumarin: a fluorescence ...
网页The interaction between thyroxine hormone and 7 hydroxycoumarin (7HC) was investigated using fluorescence quenching method. The experimental results showed that thyroxine could quench the fluorescence of 7HC by forming the 7HC …
Investigation of Binding Properties of Umbelliferone (7Hydroxycoumarin ...
网页2012年12月8日 · In the present study, 7HC was used as small molecule and studied the binding properties of lysozyme-7HC by UV–vis absorption and fluorescence quenching. The binding parameters, thermodynamic functions, intermolecular distance and the effect of common metal ions on the binding constant of lysozyme-7HC were investigated.