Aldicarb: Toxicity, Exposure and Risks to Humans - ScienceDirect
网页2010年1月1日 · Aldicarb has high acute toxicity, causing cholinergic symptoms due to the inhibition of acetylcholinesterase (AChE). These symptoms are dose-dependent, are rapidly reversible, and do not occur at expected human exposure levels. Aldicarb is neither genotoxic nor carcinogenic.
Aldicarb - Wikipedia
网页Aldicarb is a carbamate insecticide which is the active substance in the pesticide Temik. It is effective against thrips, aphids, spider mites, lygus, fleahoppers, and leafminers, but is primarily used as a nematicide. [2] Aldicarb is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse.
Acetylcholinesterase inhibitor - Wikipedia
网页Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, [1] inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate, [2] thereby increasing both the level and duration of action of acetylcholine in the central nervous system, autonomic ganglia and neurom...
Aldicarb - Occupational Exposures in Insecticide Application, and …
网页Aldicarb is highly acutely toxic: it is one of the most potent cholinesterase-inhibiting carbamate insecticides. No data were available on the genetic and related effects of aldicarb in humans. Aldicarb induced chromosomal aberrations in rat bone-marrow cells in …
Aldicarb - an overview | ScienceDirect Topics
网页Aldicarb is an N-methyl carbamate insecticide that rapidly and reversibly inhibits acetylcholinesterase, the enzyme responsible for metabolizing the neurotransmitter acetylcholine at cholinergic nerve terminals.
Toxicology of Aldicarb - SpringerLink
网页Aldicarb is a potent acetylcholinesterase inhibitor and is commercially available only in granular formulations containing 5% to 10% active ingredient. As formulated, the potential hazard of aldicarb to human health and to the environment is sinificantly reduced. Download to read the full chapter text.
Aldicarb-induced Paralysis Assay to Determine Defects in Synaptic ...
网页2017年7月7日 · Aldicarb is an acetylcholinesterase inhibitor. In the presence of aldicarb, acetylcholine continues to accumulate, causing persistent muscle contraction and eventual paralysis.
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ALDICARB
网页Aldicarb is an oxime carbamate insecticide, nematicide and acaricide. Aldicarb and its main biologically active metabolites (aldicarb sulfoxide and aldicarb sulfone) are systemic pesticides. European Community: All intended uses were related to the soil application of granular formulations. Harmful organisms to be controlled covered a large ...
网页Aldicarb is one of the most acutely toxic pesticides in use, although the only con-sistently observed toxic effect with both long-term and single-dose administration is acetylcholinesterase inhibition. It is converted to the sulfoxide and sulfone.
网页Aldicarb (2-methyl-2[methylthio]propionaldehyde O-[methyl carbamoyl] oxime; TEMIK®, Rhone-Poulenc's registered trademark) effectively con trols a wide variety of insects, mites, and nematodes and is used worldwide on more than 40 economically important crops.
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