Preparation and Characterization of Collagen–Hyaluronic Acid (Col–HA …
网页2023年12月2日 · Collagen-I (Col) and hyaluronic acid (HA) are two of the most important extracellular matrix (ECM) components. While collagen serves as the main structural feature of the ECM and is an important ligand for integrin-based …
Fabrication and characterization of microstructure-controllable COL-HA ...
网页2021年8月18日 · This research aimed to design novel hydroxyapatite (HA)-collagen (COL)-PVA hydrogels. COL was added to improve cell biocompatibility, and the microstructure of the hydrogels was controlled by fused deposition modeling (FDM). The feasibility of the COL-HA-PVA hydrogels in cartilage repair was evaluated by in vitro and in vivo experiments.
From crosslinking strategies to biomedical applications of …
网页2023年3月15日 · Hyaluronic acid (HA) is not only a natural anionic polysaccharide with excellent biocompatibility, biodegradability, and moisturizing effect, but also an essential factor that can affect angiogenesis, inflammation, cell behavior, which has a wide range of applications in the biomedical field.
Preparation and Characterization of Collagen-Hyaluronic Acid (Col-HA ...
网页Collagen-I (Col) and hyaluronic acid (HA) are two of the most important extracellular matrix (ECM) components. While collagen serves as the main structural feature of the ECM and is an important ligand for integrin-based adhesions, HA acts as a ligand for the transmembrane glycoprotein CD44.
Fabrication and characterization of microstructure-controllable COL-HA …
网页2021年8月18日 · This research aimed to design novel hydroxyapatite (HA)-collagen (COL)-PVA hydrogels. COL was added to improve cell biocompatibility, and the microstructure of the hydrogels was controlled by fused deposition modeling (FDM). The feasibility of the COL-HA-PVA hydrogels in cartilage repair was evaluated by in …
Schematic illustration for the preparation of COL-HA, its SEM …
网页Context 1. ... shown in Figure 1A, collagen-hyaluronate composite gradient membrane (COL-HA) was prepared through unidirectional freeze-drying and cross-linking technology.
Collagen- and hyaluronic acid-based hydrogels and their biomedical ...
网页2021年10月1日 · In physically crosslinked collagen and HA blend (ColHA) hydrogels, collagen molecules aggregate due to electrostatic and hydrophobic interactions to form fibrils, whereas HA can associate with the surface of collagen fibrils or occupy interstitial space and influence the microstructure and viscosity of the hydrogel (see Section 5.1.2) [[13 ...
Preparation and biological properties of collagen/nano …
网页2020年10月5日 · Based on the ordered nHA ceramic fibers, Col/HA composite nanofiber is successfully prepared by a low-cost method. • The sintering mechanism of nHA ceramic fibers was proposed. • The aligned Col/HA nanofibers biocomposite have favorable properties of mineralization, degradation and protein adsorption. •
In situ formed collagen-hyaluronic acid hydrogel as biomimetic ... - PubMed
网页The preparation of hydrogel (COL-HA) was realized through in situ coupling of phenol moieties of collagen I-hydroxybenzoic acid (COL-P) and hyaluronic-acid-tyramine (HA-Tyr) through horseradish peroxidase (HRP). The physical structure and properties were characterized, and the biological performances were analyzed.
Fabrication and characterization of microstructure-controllable COL-HA ...
网页2021年9月1日 · This research aimed to design novel hydroxyapatite (HA)-collagen (COL)-PVA hydrogels. COL was added to improve cell biocompatibility, and the microstructure of the hydrogels was controlled by...