Applying Hot-Stage Microscopy to Co-Crystal Screening: A Study …
网页Co-crystal screening is routinely undertaken using high-throughput solution growth. We report a low- to medium-throughput approach, encompassing both a melt and solution crystallization step as a route to the identification of co-crystals. Prior to solution studies, a melt growth step was included utilizing the Kofler mixed fusion method.
Highly efficient color-tunable organic co-crystals unveiling ...
网页2023年10月20日 · Photofunctional co-crystal engineering strategies based on donor-acceptor π-conjugated system facilitates expedient molecular packing, consistent morphology, and switchable optical properties,...
Cold photo-carving of halogen-bonded co-crystals of a dye and a ...
网页2022年3月31日 · Here we describe co-crystallization as a route to obtain crystalline organic materials that can be engraved, cut and/or punctured without chemical damage, and with micrometre-scale precision,...
Structurally diverse macrocycle co-crystals for solid-state ... - Nature
网页2024年3月21日 · The co-crystals are constructed using triangular pyrene-macrocycle and 1,2,4,5-tetracyanobenzene exploiting exo-wall charge-transfer interactions. Interestingly, the three co-crystals exhibit...
Simultaneous screening and detection of pharmaceutical co …
网页2017年4月1日 · This unique DSC–FTIR microspectroscopy method is a simple, quick and time-saving tool that involves a one-step continuous process that not only possibly enables co-crystal formation but also simultaneously detects the co-crystal formed via correlation between the thermal response and the informative infrared (IR) spectra of the structural ...
Nano Organic Co-Crystal Scintillator for X-ray Imaging
网页2023年4月29日 · This work demonstrates the feasibility of microstructured organic halogen-bonded co-crystal scintillator for X-ray imaging, providing new insight into the development of ideal scintillators.
Applying Hot-Stage Microscopy to Co-Crystal Screening: A Study …
网页2008年4月25日 · Co-crystal screening is routinely undertaken using high-throughput solution growth. We report a low- to medium throughput approach, encompassing both a melt and solution crystallization step as a...
Hot stage microscopy and its applications in pharmaceutical ...
网页2020年6月16日 · Hot stage microscopy (HSM) is a thermal analysis technique that combines the best properties of thermal analysis and microscopy. HSM is rapidly gaining interest in pharmaceuticals as well as in other fields as a regular characterization technique.
网页Applying hot -stage microscopy to co -crystal screening: a study of nicotinamide with seven active pharmaceutical ingredients - Supplementary information. This section contains; 1. Crystallization specifics for solvent screening 2. Kofler hot -stage results 3. Torsion angles of nicotinamide dimers and the structures they appear in.
Applying Hot-Stage Microscopy to Co-Crystal Screening: A Study …
网页2008年5月7日 · A low- to medium-throughput approach, encompassing both a melt and solution crystallization step as a route to the identification of co-crystal systems, is reported, finding three new co-Crystal systems have been …