Coumarin - Wikipedia
网页Coumarin is a colorless crystalline solid with a sweet odor resembling the scent of vanilla and a bitter taste. [1] It is found in many plants, where it may serve as a chemical defense against predators. Coumarin inhibits synthesis of vitamin K, …
An Overview of Coumarin as a Versatile and Readily Accessible …
网页2020年6月29日 · Privileged structures have been widely used as an effective template for the research and discovery of high value chemicals. Coumarin is a simple scaffold widespread in Nature and it can be found in a considerable number of plants as well as in some fungi and bacteria.
Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive ...
网页2018年1月27日 · Many naturally occurring substances, traditionally used in popular medicines around the world, contain the coumarin moiety. Coumarin represents a privileged scaffold for medicinal chemists, because of its peculiar physicochemical features, and the versatile and easy synthetic transformation into a large variety of functionalized coumarins.
Coumarin | C9H6O2 | CID 323 - PubChem
网页Coumarin | C9H6O2 | CID 323 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Natural Coumarins: Exploring the Pharmacological Complexity …
网页2021年8月23日 · Many plants contain different concentrations of coumarin. Tonka beans, liquorice, and cassia cinnamon have a high concentration of natural coumarins. Some cherry blossom strawberries and apricots contain coumarin in smaller quantities.
Coumarin: Uses, Interactions, Mechanism of Action - DrugBank …
网页The risk or severity of bleeding can be increased when Omega-3-acid ethyl esters is combined with Coumarin. Omega-3-carboxylic acids. The therapeutic efficacy of Coumarin can be increased when used in combination with Omega-3-carboxylic acids. Ondansetron.
A review on applications of coumarin and its ... - ScienceDirect
网页2023年10月17日 · Photoresponsive polymers have garnered significant interest due to their potential applications in a wide range of fields, from self-healing materials to drug …
Coumarin—Synthetic Methodologies, Pharmacology, and …
网页2024年5月9日 · Coumarins as fluorophores play a key role in fluorescent labeling of biomolecules, metal ion detection, microenvironment polarity detection, and pH detection. This review provides a detailed insight into the characteristics of coumarins as well as their biosynthesis in plants and metabolic pathways.
Coumarin: A Natural, Privileged and Versatile Scaffold for …
网页The simpler, yet straightforward way to prepare multitarget ligands (Figure 26) consists in attaching two pharmacophoric moieties, responsible for two diverse bio-pharmacological activities, by means of a stable or metabolically cleavable linker (conjugation), or by a direct covalent bond formation (fusion).
The structure and pharmacological functions of coumarins and …
网页Coumarins are of many different structures. They constitute an important class of pharmacological agents possessing a range of different physiological activities including anti-cancer, anti-oxidant, anti- inflammation, anti-HIV, anti-coagulant, anti-bacterial, analgesic and comparative immune-modula ….