Degenerative Disk Disease: Causes, Symptoms & Treatment - Cleveland Clinic
网页Degenerative disk disease occurs when your spinal disks break down. When these disks wear out, people typically experience back pain and stiffness. You may find pain relief with nonsurgical treatments such as physical therapy and spinal injection.
Lumbar Degenerative Disc Disease (DDD) - Spine-health
网页Degenerative disc disease in the lumbar spine, or lower back, refers to a syndrome in which age-related wear and tear on a spinal disc causes low back pain.
Lumbar Degenerative Disk Disease - StatPearls - NCBI Bookshelf
网页2023年8月4日 · Objectives: Describe the pathophysiology of lumbar degenerative disc disease. Outline the components of proper evaluation and assessment of a patient presenting with lumbar degenerative disc disease, including any indicated imaging studies. Review the treatment and management …
A Brief Review of the Degenerative Intervertebral Disc Disease
网页2019年10月12日 · The main factor in the degeneration of the intervertebral disc is the loss of proteoglycans. Degenerative changes of the disc are connected to damage of adjacent structures, leading to functional changes, higher susceptibility to injuries and clinical signs and symptoms. Conclusions:
Current Understanding of Lumbar Intervertebral Disc Degeneration…
网页2008年6月1日 · Degeneration of the lumbar intervertebral discs (IVDs) is highly prevalent in adults and nearly universal in the elderly population. Degenerative changes within, and adjacent to, the IVDs are likely to contribute to a variety of pain syndromes; however, the exact association between these findings and symptoms remains speculative.
Painful intervertebral disc degeneration and inflammation: …
网页2021年1月29日 · The suppression of LBP is a primary goal of clinical practice but has not received enough attention in disc research studies. Here, an overview of the advances in inflammation-related pain in...
Recent Advances in Managing Spinal Intervertebral Discs Degeneration
网页2022年6月9日 · The major cause of LBP is intervertebral disc degeneration (IDD), a complex disease that can further aggravate and give rise to severe spine problems.
Fundamentals of Intervertebral Disc Degeneration - PubMed
网页Lumbar disc degeneration is one of the leading causes of chronic low back pain. The degenerative cascade is often initiated by an imbalance between catabolic and anabolic processes in the intervertebral discs. As a consequence of extracellular matrix degradation, neoinnervation and neovascularization take place.
Mechanisms and clinical implications of intervertebral disc
网页2022年5月9日 · Intervertebral disc (IVD) calcification is associated with IVD degeneration and can lead to pain. IVD calcification may affect disc kinematics and degeneration severity, and can also...
Degenerative Disk Disease: Symptoms, Causes, Diagnosis, Treatment - WebMD
网页2023年10月25日 · Lumbar degenerative disk disease. Your lower back, or lumbar spine, has five vertebrae, which are the largest bones in your back. Doctors refer to them as L1 to L5.