Linezolid-Induced Toxic Optic Neuropathy - PMC - National …
网页2021年1月19日 · Common etiologies known to cause toxicity are drugs (Ethambutol, Amiodarone, and Tamoxifen) and nutritional deficiencies (Vitamin B12, folate). We report a case of bilateral toxic optic neuropathy in a 25-year-old male known to have extensive drug-resistant tuberculosis (XDR-TB) presented with bilateral sudden visual …
Visual electrophysiology in the assessment of toxicity and …
网页2021年7月21日 · The toxicity of ethambutol may be potentiated by renal impairment or co-administration of other drugs which can cause optic neuropathy in their own right, such as linezolid or isoniazid .
Linezolid-induced optic neuropathy - PMC - National Center for ...
网页2012年6月27日 · We describe a case of progressive loss of vision associated with linezolid therapy. A 45-year-old male patient who was on treatment with multiple second-line anti-tuberculous drugs including linezolid and ethambutol for extensively drug-resistant tuberculosis (XDR-TB) presented to us with painless progressive loss of vision in both eyes.
Ethambutol toxicity: Expert panel consensus for the primary …
网页2021年11月26日 · Ethambutol use may lead to permanent vision loss by inducing a dose- and duration-dependent optic neuropathy. This has been of concern to ophthalmologists and physicians both; however, ethambutol continues to be used because of its anti-mycobacterial action with relative systemic safety.
Ethambutol Optic Neuropathy - EyeWiki
网页Ethambutol (EMB) is an antibiotic used to treat infection by Mycobacterium species, particularly Mycobacterium tuberculosis and non- tubercular infections like M. avium complex and M. kansasii. Unfortunately, one serious and vision threatening side effect of EMB is ethambutol-induced optic neuropathy (EON). [1]
Linezolid-induced optic neuropathy : Indian Journal of …
网页2012年6月27日 · We describe a case of progressive loss of vision associated with linezolid therapy. A 45-year-old male patient who was on treatment with multiple second-line anti-tuberculous drugs including linezolid and ethambutol for extensively drug-resistant tuberculosis (XDR-TB) presented to us with painless progressive loss of vision in both eyes.
Toxic Optic Neuropathy - EyeWiki
网页Linezolid: Prolonged linezolid usage can interfere with mammalian ribosomes and lead to the disruption of mitochondrial oxidative phosphorylation and protein synthesis. Ethambutol: The chelating property of ethambutol has adverse effects on human cells.
Ethambutol/Linezolid Toxic Optic Neuropathy - PubMed
网页Ethambutol. Linezolid. Drug-associated toxic optic neuropathy is a rare but vision-threatening condition. Diagnosis is made based on an extensive case history and careful clinical examination. The examination findings include varying decrease in vision, normal pupils and extraocular muscles, and unremarkable fundoscopy, w ….
(PDF) Consensus Statement Ethambutol toxicity: Expert panel …
网页2021年11月25日 · Ethambutol use may lead to permanent vision loss by inducing a dose- and duration-dependent optic neuropathy. This has been of concern to ophthalmologists and physicians both; however,...
Ocular Ethambutol Toxicity - Mayo Clinic Proceedings
网页This case and a review of the literature show the severe and unpredictable nature of ethambutol toxicity and its potential for irreversible vision loss despite careful ophthalmologic monitoring. Ethambutol hydrochloride is a bacteriostatic antimicrobial agent used as a first-line defense against tuberculosis (TB).