Gums as Pharmaceutical Excipients: An Overview | SpringerLink
网页2022年2月16日 — In drug delivery, gum mastic has been used in film-forming, enteric coating, matrix system, controlled release of the drug, and stability enhancement [1, 9, 22,23,24,25]. In a study by Stefka Koychev and coworkers, chewing mastic gum was proven to be a good antiplaque agent that decreases bacterial growth in saliva and plaque production on teeth.
Innovations in Chewable Formulations: The Novelty and …
网页2022年8月18日 — Many of the excipients used to prepare chewable tablets are similar to those used in conventional tablets (Table 1). The key excipients in chewable tablets include flavouring agents and sweeteners because they are intended to be chewed, and it is necessary to mask unpleasant tastes.
Chewing Gums as a Drug Delivery Approach for Oral Health
网页2022年6月20日 — Chewing gum can be used to provide a controlled dose of an active component to the mouth. Chewing gum active compounds are released in a variety of ways, depending on parameters such as chewing speed, gum base concentration, and active ingredient solubility in water, allowing them …
Medicated Chewing Gums (MCGs): Composition, Production, …
网页2018年8月7日 — Generally, chewing gums are made by combining two phases: (1) a continuous water-soluble phase that contains nonmasticatory ingredients, such as an API, plasticizers, flavors, and sweetening agents; and (2) an insoluble discontinuous phase (tasteless masticatory gum base), which mainly contains the gum base as the fundamental material that is ...
Medicated chewing gum | American Journal of Drug Delivery
网页2012年8月20日 — Several ingredients are now incorporated in medicated chewing gum, e.g. fluoride for prophylaxis of dental caries, chlorhexidine as a local disinfectant, nicotine for smoking cessation, aspirin (acetylsalicylic acid) as an analgesic, dimenhydrinate for motion sickness, and caffeine as a ’stay alert’ preparation.
Design, formulation, and evaluation of ginger medicated chewing gum
网页2016年7月29日 — Chewing gums containing 50 mg of concentrated extract were prepared. Content uniformity, weight variation, release pattern, organoleptic, and mechanical properties were evaluated. Results: Phenolic content was measured 61.50 ± 5.27 mg/g and 76.75 ± 5.45 mg/g of concentrated extract as gallic acid …
Formulation development of medicated chewing gum tablets …
网页2019年11月1日 — MCG are most commonly manufactured by using the traditional hot melting/extrusion method, which includes heating of the gum base, addition of API and excipients, followed by cutting the chewing gums into pieces after cooling. This method is time consuming and of limited use for substances sensitive to moisture and heat.
网页We classify these formulations into several categories: traditional medicated gums, which depend on straightforward dissolution and absorption mechanisms; sustained-release gums, which use specialized matrices to regulate the release of the drug over extended periods; and bioadhesive gums, which improve drug retention and localized effects.
Flavor Microencapsulation for Taste Masking in Medicated Chewing …
网页2022年10月31日 — Flavor encapsulation slows down the interactions between the chewing gum excipients, the presence of oxygen radicles, and various environmental changes. The controlled-release chewing gum of caffeine was formulated by tangibly modifying caffeine’s characters by spray-drying microencapsulation .
Medicated chewing gum - PharmTech
网页2010年1月1日 — Cafosa has developed a new excipient, Health in Gum — a directly compressible powder gum containing a mix of ingredients to which APIs can be added. To date, Health in Gum is being used by customers as a way to differentiate their products in a very competitive market and to provide added value to consumers.
- 某些结果已被删除