Indazole - Wikipedia
网页Indazole, also called isoindazole, is a heterocyclic aromatic organic compound. This bicyclic compound consists of the fusion of benzene and pyrazole. Indazole is an amphoteric molecule which can be protonated to an indazolium cation or …
Indazole: a medicinally important heterocyclic moiety
网页2011年4月12日 · Indazole, also called benzpyrazole or isoindazone (1), is a heterocyclic aromatic organic compound with a rare occurence in nature. The family of nitrogen-containing heterocycles, especially the structurally diverse indazole nuclei, has aroused great interest in the past as well as in the recent years bacause of …
吲唑 - 维基百科，自由的百科全书
网页13.86 (酸性)1.25 (碱性) 若非注明，所有数据均出自 标准状态（25 ℃，100 kPa） 下。. 吲唑 （英語： Indazole），即1,2-二氮杂 茚；苯并 吡唑。.
Indazoles: Synthesis and Bond-Forming Heterocyclization
网页2018年1月1日 · Abstract. Indazoles (azaindoles) are heterocyclic compounds structurally related to indoles and can be viewed as indole isosteres. The indazole moiety is a 10-π electron aromatic heterocyclic system. Like the pyrazole, indazole resembles both pyridine and pyrrole and its reactivity reflects this.
Indazole - an overview | ScienceDirect Topics
网页Indazole is a bicyclic heteroaromatic nitrogen heterocycle, constituted by fusion of benzene with the “d” site of the 1,2-azole (pyrazole) ring. From: The Chemistry of Heterocycles, 2019
Recent Advances in Indazole-Containing Derivatives: Synthesis …
网页2018年10月26日 · Indazole-containing derivatives represent one of the most important heterocycles in drug molecules. Diversely substituted indazole derivatives bear a variety of functional groups and display versatile biological activities; hence, they have gained considerable attention in the field of medicinal chemistry.
A review on synthetic strategy, molecular pharmacology of indazole ...
网页2022年8月16日 · Indazole, an important fused aromatic heterocyclic system containing benzene and pyrazole ring with a chemical formula of C 7 H 6 N 2, is also called benzopyrazole. Indazoles consist of three tautomeric forms in which 1 H -tautomers (indazoles) and 2 H -tautomers (isoindazoles) exist in all phases.
Indazole and its Derivatives in Cardiovascular Diseases: Overview ...
网页Many indazole derivatives have shown potential beneficial effects against cardiovascular and metabolic diseases such as arrhythmia, ischemia-reperfusion injury, thrombosis, hypertension, hyperlipidemia, and obesity. One of the most promising indazole derivatives, DY-9760e, has shown cardioprotection against ischemic/reperfusion injury .
Current progress, challenges and future prospects of indazoles as ...
网页2021年7月7日 · Indazole derivatives are applied for the targeted treatment of lung, breast, colon, and prostate cancers. In this review, we compile the current development of indazole derivatives as kinase inhibitors and their application …
Indazole | C7H6N2 | CID 9221 - PubChem
网页Indazole | C7H6N2 | CID 9221 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.