NS-398, a new anti-inflammatory agent, selectively inhibits ... - PubMed
网页NS-398 is a novel anti-inflammatory and analgesic agent which produces much fewer gastrointestinal lesions in rats. Recently, two forms of cyclooxygenase have been identified: a COX-1 first purified from ram seminal vesicles and a newly discovered mitogen-inducible form (COX-2).
NS-398 | COX-2抑制剂 | MCE - MCE-生物活性分子大师
网页NS-398 是一种非甾体类抗炎剂，具有解热作用，可用于缓解疼痛的研究。 NS-398 能够选择性地抑制 COX-2 的活性， IC50 值为 3.8 μM，在 100 μM 的浓度下，对 COX-1 的活性没有作用。 MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务. NS-398 Chemical Structure. CAS No. : 123653-11-2. or 大包装询价. * Please select Quantity before adding items. Customer Review. MCE 顾客使用本产品发表的 14 篇科研文献. • …
NS-398 - Wikipedia
网页NS-398 is a COX-2 inhibitor used in the study of the function of cyclooxygenases. See also. Celecoxib; Tilmacoxib (JTE-522) References
The cyclooxygenase-2 inhibitor NS-398 inhibits proliferation and ...
网页The present study aimed to investigate the expression and clinical significance of COX-2 and survivin (SUV) in human osteosarcomas (OS), and explore the effects and molecular mechanisms of a selective COX-2 inhibitor NS-398 and …
Cyclooxygenase-2 selective inhibition with NS-398 suppresses …
网页2004年2月3日 · NS-398 (100 μ M), a highly selective COX-2 inhibitor, decreased cell proliferation by ∼35% of control, as determined using [3H]-thymidine incorporation.
NS-398, a novel non-steroidal anti-inflammatory drug with potent ...
网页1. NS-398 (N-[2-cyclohexyloxy-4-nitrophenyl] methanesulfonamide) is a new non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic effects. 2. The anti-inflammatory potency of NS-398 in rat carrageenin-induced edema was as potent as that of indomethacin and 8 times more potent tha …
NS-398, a Cyclooxygenase-2-Specific Inhibitor, Delays Skeletal …
网页Here we examined the effects of NS-398, a Cox-2-specific inhibitor, both on myogenic precursor cells in vitro and in a mouse skeletal muscle laceration model in vivo. The administration of NS-398 inhibited the proliferation and maturation of differentiated myogenic precursor cells in vitro.
NS-398, a selective cyclooxygenase-2 blocker, acutely inhibits …
网页2003年1月1日 · NS-398 (N-(2-cyclohexyloxy-4-nitrophenyl)-methane sulfonamide) is a selective inhibitor of the cyclooxygenase-2 isozyme in vitro and in vivo. This study reports on acute inhibition of receptor-mediated contractions of isolated rat aorta by NS-398 and its modulation by endothelium-derived nitric oxide.
NS-398, a new anti-inflammatory agent, selectively inhibits ...
网页1994年1月1日 · NS-398 is a novel anti-inflammatory and analgesic agent which produces much fewer gastrointestinal lesions in rats. Recently, two forms of cyclooxygenase have been identified: a COX-1 first purified from ram seminal vesicles and a newly discovered mitogen-inducible form (COX-2).
NS-398, a new anti-inflammatory agent, selectively inhibits ...
网页1994年1月1日 · NS-398 is a novel anti-inflammatory and analgesic agent which produces much fewer gastrointestinal lesions in rats. Recently, two forms of cyclooxygenase have been identified: a COX-1 first purified from ram seminal vesicles and a newly discovered mitogen-inducible form (COX-2).
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