Protein domain - Wikipedia
网页In molecular biology, a protein domain is a region of a protein's polypeptide chain that is self-stabilizing and that folds independently from the rest. Each domain forms a compact folded three-dimensional structure. Many proteins consist of several domains, and a domain may appear in a variety of different proteins.
InterPro - EMBL-EBI
网页InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.
3.6: Protein Domains, Motifs, and Folds in Protein Structure
网页Domain names often derive from their prominent biological function in the protein they belong to (e.g., the calcium-binding domain of calmodulin), or from their discoverers (the PH domain!). The domain swapping that gives rise to gene families and superfamilies are natural genetic events.
蛋白质结构域 - 维基百科，自由的百科全书
网页蛋白质结构域 （英語： protein domain）是 蛋白质 多肽链 中具有特异结构和独立功能的区域，能自稳定，独立于其他区域折叠，其构成蛋白质 三级结构 的基本单元。. 每个结构域形成一个紧凑的折叠三维结构。. 许多蛋白质由几个结构域组成，而一个结构域可能 ...
What are protein domains? | Protein classification - EMBL-EBI
网页Domains are distinct functional and/or structural units in a protein. Usually they are responsible for a particular function or interaction, contributing to the overall role of a protein. Domains may exist in a variety of biological contexts, where similar domains can be found in proteins with different functions.
Protein domain identification methods and online resources
网页2021年2月2日 · Protein domains are the basic units of proteins that can fold, function, and evolve independently. Knowledge of protein domains is critical for protein classification, understanding their biological functions, annotating their evolutionary mechanisms and protein design.
Expasy - PROSITE
网页2024年7月24日 · PROSITE consists of documentation entries describing protein domains, families and functional sites as well as associated patterns and profiles to identify them [More... / References / Commercial users ]. PROSITE is complemented by ProRule , a collection of rules based on profiles and patterns, which increases the …
The Shape and Structure of Proteins - Molecular Biology of the …
网页This is the protein domain, a substructure produced by any part of a polypeptide chain that can fold independently into a compact, stable structure. A domain usually contains between 40 and 350 amino acids, and it is the modular unit …
NCBI's Conserved Domain Database and Tools for Protein Domain …
网页2019年12月18日 · A protein domain is typically associated with a function, such as enzyme catalysis or nucleic‐acid binding, and is a unit of molecular evolution; via comparative sequence analysis, protein domain sequences can …
NCBI Protein Domains and Macromolecular Structures
网页Conserved domains are functional units within a protein that act as building blocks in molecular evolution and recombine in various arrangements to make proteins with different functions.
跳至内容