SC-560 | COX 抑制剂 | 现货供应 | 美国品牌 | 免费采购电话400-668 …
网页sc-560 是一种高度选择性的 cox-1 抑制剂，ic50值为9 nm，而对于 cox-2 的ic50值为6.3μm 比 cox-1 高近1,000倍。 靶点 COX-1 [1]
SC-560 | COX-1 抑制剂 | MCE - MCE-生物活性分子大师
网页在测定前 1 小时口服 10 或 30 mg/kg SC-560 可完全抑制离子载体刺激的 TxB2 产生，表明 SC-560 具有口服生物利用度并在体内抑制 COX-1 。SC-560 广泛分布于大鼠组织中，CL 接近肝血浆流量。
SC-560, COX-1 inhibitor (CAS 188817-13-2) (ab120649) - Abcam
网页SC-560, COX-1 inhibitor. MW 352.7 Da, Purity >99%. Highly selective cyclooxygenase-1 (COX-1) inhibitor (IC 50 values are 9 nM and 6.3 μM for COX-1 and COX-2, respectively). Displays anti-inflammatory, antitumor and antiviral activity. Orally active.
网页SC-560 is novel, potent, and highly selective inhibitor of cyclooxygenase-1 (COX-1). The enzymes COX-1 and COX-2 catalyze the conversion of arachidonic acid to prostaglandin H2 (PGH2), the precursor of other PGs and thromboxane.1 These lipid mediators play important roles in inflammation and pain, as well as in normal physiological functions.
SC-560 | COX-1 Inhibitor - MedChemExpress
网页SC-560 shows a dose and time dependent inhibitory effect on HCC cell growth. SC-560 also inhibits colony formation in soft agar and induces apoptosis in HCC cells in a dose-dependent manner. Moreover, SC-560 decreases the levels of the anti-apoptotic proteins survivin and XIAP and activates caspase 3 and 7 in a dose and time dependent fashion [2] .
SC-560，COX-1抑制剂(ab120649) - Abcam中文官网
网页概述. 产品名称. SC-560，COX-1抑制剂. 描述. Highly selective COX-1抑制剂. 生物学描述. Highly selective cyclooxygenase-1 (COX-1) inhibitor (IC 50 values are 9 nM and 6.3 μM for COX-1 and COX-2, respectively). Displays anti-inflammatory, antitumor and antiviral activity. Orally active. 纯度. > 99% CAS编号. 188817-13-2. 化学结构. 性能. 图片. 实验方案. 数据表及 …
SC-560 | COX-1 Inhibitor | AmBeed-信号通路专用抑制剂
网页99%+. SC-560 is a highly selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 0.009 and 6.3 μM for COX-1 and COX-2 respectively). It inhibits COX-1-derived platelet thromboxane B2, gastric PGE2 and dermal PDE2 production and significantly reduces ovarian surf ace epithelial tumor growth in vivo.
SC-560 (CAS 188817-13-2) - Cayman Chem
网页SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors which includes celecoxib (Celebrex™) and rofecoxib (Vioxx™). However, unlike these selective COX-2 inhibitors, SC-560 is a selective inhibitor of COX-1.
SC 560 Supplier | CAS 188817-13-2 | SC560 | Tocris Bioscience
网页SC 560 is a highly selective cyclooxygenase-1 (COX-1) inhibitor (IC 50 values are 0.009 and 6.3 μ M for COX-1 and COX-2 respectively). Inhibits COX-1-derived platelet thromboxane B 2, gastric PGE 2 and dermal PDE 2 production. Significantly reduces ovarian surface epithelial tumor growth in vivo. Orally active.
- 评论数: 1
SC-560 | COX | TargetMol
网页sc-560展示了剂量和时间依赖性地抑制hcc细胞生长的效应。 同时，SC-560在剂量依赖的方式下抑制软琼脂中的集落形成，并诱导HCC细胞发生凋亡。 此外，SC-560降低了抗凋亡蛋白survivin和XIAP的水平，并在剂量和时间依赖的方式中激活caspase 3和7。