可溶性白细胞介素-2受体 - 百度百科
网页可溶性白细胞介素-2受体 (soluble interleukin-2 receptor，SIL-2R)是一种复合性粘蛋白，同时具有与抗Tac单抗和白细胞介素-2结合的信息，与白细胞介素-2结合不需任何辅助因子，可溶性白细胞介素-2受体是一种重要的免疫抑制剂，可中和活化T细胞周围的白细胞介素-2 ...
SIL-2R - 百度百科
网页SIL-2R. 可溶性白细胞介素-2 受体（soluble interleukin-2 receptor，可溶性白细胞介素2受体）是一种复合性粘蛋白，同时具有与抗Tac单抗和白细胞介素-2结合的信息，与白细胞介素-2结合不需任何辅助因子，可溶性白细胞介素-2受体是一种重要的免疫抑制剂，可中和活化T ...
Clinical significance of soluble interleukin-2 receptor ... - PubMed
网页A soluble form of the interleukin-2 receptor (sIL-2R) is secreted upon T-cell activation. Increased blood levels of sIL-2R occur in a variety of immunological diseases. Although the biological function of sIL-2R is incompletely understood, both in health and disease, sIL-2R serum measurements are co ….
The IL-2 – IL-2 receptor pathway in health and ... - ScienceDirect
网页2020年9月1日 · The role of sIL-2R in the interplay of the IL-2 – IL-2R pathway in immunity and tolerance, however, remains controversial. sIL-2R may either function as a decoy-receptor that reduces the bio-availability of IL-2, or it enables in trans activation by presenting IL-2 to dimeric IL-2R expressing immune cells.
Serum soluble interleukin-2 receptor levels for screening for …
网页2019年9月11日 · The serum soluble interleukin 2 receptor (sIL2R) level is elevated in patients with most types of lymphoid neoplasms, and is also elevated in patients with solid tumors or reactive conditions, such as severe inflammation.
The IL-2 – IL-2 receptor pathway: Key to understanding multiple ...
网页2021年9月21日 · Multiple studies demonstrated that the interleukin (IL)-2 – IL-2 receptor (IL-2R) pathway plays a pivotal role within these processes. The most striking functions of the IL-2 – IL-2R pathway are the differential induction of …
Potential contribution of increased soluble IL-2R to ... - Nature
网页2020年6月25日 · Circulating sIL-2R has been shown to regulate T-lymphocyte activation in various immunological disorders and increased sIL-2R concentration in plasma predicts a decreased cellular response to...
Clinical utility of soluble interleukin-2 receptor in ... - PubMed
网页The serum-soluble interleukin-2 receptor (sIL-2r) level is considered an important diagnostic test and disease marker in hemophagocytic syndromes/hemophagocytic lymphohistiocytosis (HPS/HLH). However, this cytokine receptor is rarely measured in clinical practice and has been excluded from recent di …
Performance of serum soluble interleukin-2 receptor as a ... - Nature
网页2023年11月1日 · Soluble interleukin-2 receptor (sIL-2R), which is the cleaved chain of the IL-2 receptor alpha (also known as CD25) on the cell membrane due to proteolytic processing,...
Serum soluble interleukin-2 receptor (sIL-2R) is an accurate …
网页2022年8月23日 · Serum soluble interleukin-2 receptor (sIL-2R) is an accurate biomarker for dengue-associated hemophagocytic lymphohistiocytosis syndrome diagnosed by Hscore. Chakrapani Mahabala, 1,5 Vivek K. Koushik, 2 Poornima A. Manjrekar, 3,5 and Prashantha Balanthimogru 4,5.
跳至内容