Sickle Cell Disease - Sickle Cell Trait - NHLBI, NIH
网页2024年8月22日 · Most people living with sickle cell trait have no symptoms and lead normal lives. It is rare for people with sickle cell trait to have complications from the condition, but a few do. Scientists are working to better understand when and how sickle cell trait might affect a person’s health. Sickle cell trait does not shorten a person’s lifespan.
Sickle Cell Disease - Symptoms | NHLBI, NIH
网页2024年8月20日 · Serious pain linked with sickle cell disease often requires treatment in a clinic or hospital. Fatigue (extreme tiredness), shortness of breath, dizziness, and irregular heartbeat. These are symptoms of serious anemia. Life-threatening anemia can be caused by conditions such as a splenic sequestration crisis crisis or an aplastic crisis .
Sickle Cell Disease - What Is Sickle Cell Disease? - NHLBI, NIH
网页2024年9月30日 · Sickle cell disease — also called sickle cell anemia — is a group of inherited disorders that affect hemoglobin , the major protein that carries oxygen in red blood cells. Normally, red blood cells are disc-shaped and flexible so they can move easily through the blood vessels. In sickle cell disease, red blood cells are misshaped, typically ...
Sickle Cell Disease - Treatment - NHLBI, NIH
网页2024年9月30日 · View fact sheet. Crizanlizumab-tmca is approved for adults and children ages 16 years and older who have sickle cell disease. The medicine is given through an intravenous (IV) line in the vein once a month. The medicine helps prevent blood cells from sticking to blood vessel walls and blocking blood flow.
Sickle Cell Disease - Causes and Risk Factors - NHLBI, NIH
网页2024年8月20日 · This child has sickle cell trait and is a carrier of the hemoglobin S gene. A 25%, or 1 in 4, chance of inheriting two hemoglobin S genes. This child has sickle cell disease. It is important to keep in mind that each time this couple has a child, the chances of that child having sickle cell disease remain the same.
How Sickle Cell Disease May Affect Your Health - NHLBI, NIH
网页2024年8月22日 · It filters your blood and destroys old blood cells. In people who have sickle cell disease, red blood cells may get trapped in the spleen. This makes the spleen quickly grow larger than normal. Serious anemia can occur when red blood cells get trapped in the spleen. A large spleen may also cause pain in the left side of the belly.
Questions and answers about sickle cell trait | NHLBI, NIH
网页The National Heart, Lung, and Blood Institute (NHLBI) is currently defining which research questions need to be answered about sickle cell trait. In June 2010, the NHLBI and the Advisory Committee of Blood Safety and Availability in the Office of Public Health and Science, U.S. Department of Health and Human Services, held a two-day scientific ...
Sickle Cell Disease - Diagnosis - NHLBI, NIH
网页2024年9月9日 · Prenatal screening. Healthcare providers can also diagnose sickle cell disease before a baby is born. This can be done in two ways. The first uses a sample of amniotic fluid (the liquid in the sac surrounding a growing embryo). The second uses a sample taken from the placenta (the organ that attaches the umbilical cord to the womb).
Sickle Cell Disease Fact Sheet - NHLBI, NIH
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Sickle Cell Disease Research | NHLBI, NIH
网页2024年8月23日 · Current research into sickle cell trait. People with sickle cell disease have two genes for hemoglobin S. In contrast, people with sickle cell trait have one gene for hemoglobin S and another gene for normal hemoglobin A. Though most people who have sickle cell trait don’t have any symptoms, some may experience symptoms in rare …