Silybin and the liver: From basic research to clinical practice
网页2011年5月5日 · This review analyzes the available studies on the effects of the purified product silybin, both as a free and a conjugated molecule, on liver cells or on experimentally induced liver damage, and in patients with liver disease.
Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many …
网页2017年1月24日 · Silymarin is the extract of Silybum marianum, or milk thistle, and its major active compound is silybin, which has a remarkable biological effect. It is used in different liver disorders, particularly chronic liver diseases, cirrhosis and hepatocellular carcinoma, because of its antioxidant, anti-inflammatory and antifibrotic power.
Silymarin as Supportive Treatment in Liver Diseases: A Narrative …
网页2020年2月17日 · Silymarin-Eurosil 85 is a formulation of silymarin with high oral bioavailability and potent antioxidant effects in preclinical models of liver disease. Silymarin acts as a free radical scavenger, along with modulating the enzymes responsible for the development of cellular damage, fibrosis and cirrhosis.
Silymarin/Silybin and Chronic Liver Disease: A Marriage of …
网页2017年1月24日 · Silymarin is the extract of Silybum marianum, or milk thistle, and its major active compound is silybin, which has a remarkable biological effect. It is used in different liver disorders, particularly chronic liver diseases, cirrhosis and hepatocellular carcinoma, because of its antioxidant, anti-inflammatory and antifibrotic power.
(PDF) Impact of Silymarin Supplements on Liver Enzyme Levels: A ...
网页2023年10月24日 · Silymarin showed significant effects on liver enzymes in the levels of ALP and bilirubin (P < 0.05), with no significant impact on renal function in the levels of Blood urea nitrogen (BUN) and ...
Silymarin: Unveiling its pharmacological spectrum and therapeutic ...
网页2024年2月16日 · Silymarin, a natural compound with antioxidant properties, anti-inflammatory effects, and antifibrotic activity, has shown potential in treating liver damage caused by alcohol, NAFLD, drug-induced toxicity, and viral hepatitis.
Silybin Alleviated Hepatic Injury by Regulating Redox Balance
网页2024年3月6日 · Silybin Alleviated Hepatic Injury by Regulating Redox Balance, Inflammatory Response, and Mitochondrial Function in Weaned Piglets under Paraquat-Induced Oxidative Stress. by. Long Cai. 1,†, Dongxu Ming. 1,†, Wenning Chen. 1,†, Ying Zhao. 1,2, Yanpin Li. 1, Wenjuan Sun. 1, Yu Pi. 1, Xianren Jiang. 1,* and. Xilong Li. 1,*
Silybin regulates P450s activity by attenuating endoplasmic …
网页2022年6月15日 · Our previous study showed that a hepatoprotective agent silybin restored CYP3A expression in mouse nonalcoholic fatty liver disease (NAFLD). In this study we investigated how silybin...
Silybin ameliorates hepatic lipid accumulation and modulates …
网页2020年3月1日 · Silybin ameliorates hepatic lipid accumulation and modulates global metabolism in an NAFLD mouse model. RunbinSuna, DanXub, QingliWeia, BanglingZhanga, JiyeAaa, GuangjiWanga, YuanXiea. Show more. Add to Mendeley. https://doi.org/10.1016/j.biopha.2019.109721Get rights and content. Under a Creative Commons license. open access. Abstract.
Silybin and the liver: from basic research to clinical practice
网页2011年5月14日 · This review analyzes the available studies on the effects of the purified product silybin, both as a free and a conjugated molecule, on liver cells or on experimentally induced liver damage, and in patients with liver disease.
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