Batroxobin - Wikipedia
网页Batroxobin, also known as reptilase, is a snake venom enzyme with Venombin A activity produced by Bothrops atrox and Bothrops moojeni, venomous species of pit viper found east of the Andes in South America.
巴曲酶 - 百度百科
网页巴曲酶（Batroxobin）是 WHO 对毒蛇 Bothrops atrox 蛇毒中所含的纤维蛋白促凝蛋白酶所命名的通用名。 研究发现 Bothrops atrox 有五个亚种，有一种亚种 Bothrops moojeni 蛇毒所含的巴曲酶与来自 B.atrox 蛇毒的巴曲酶在理化性质、生化特点、作用等方面均不同。
Batroxobin: Uses, Interactions, Mechanism of Action - DrugBank …
网页2014年6月17日 · Batroxobin is a defibrinogenating hemostatic agent derived from the venom of a pit viper, Bothrops atrox moojeni. In addition to batroxobin, the venom of Bothrops atrox has a composition of 10.2% neutral carbohydrate. Batroxobin is a serine protease, which cleaves the 16 Arginine - 17 Glycine bond in fibrinogen.
Use of Batroxobin in Central and Peripheral Ischemic Vascular …
网页2021年12月2日 · This review aims to summarize current study findings about batroxobin on correcting cerebral arterial, venous, and peripheral vascular diseases, to explore the mechanism of batroxobin on anti-thrombosis process.
Batroxobin - an overview | ScienceDirect Topics
网页Batroxobin is a snake venom thrombin-like enzyme which has been used for the treatment of thrombotic disorders, ischemic stroke and myocardial infraction. Batroxobin induces the cleavage of fibrinogen to a loose, easily degraded fibrin. Batroxobin decreases levels of fibrinogen and increases fibrinolytic activity [21, 82].
Batroxobin Binds Fibrin with Higher Affinity and Promotes Clot ...
网页Batroxobin is a potent defibrinogenating enzyme, which is a property that has been exploited in studies of batroxobin for prevention or treatment of thrombosis. Batroxobin binds fibrin(ogen) with high affinity, and fibrin-bound batroxobin is more potent than fibrin-bound thrombin at triggering fibrin accretion, likely because batroxobin is not ...
Use of Batroxobin in Central and Peripheral Ischemic Vascular ... - PubMed
网页2021年12月2日 · This review aims to summarize current study findings about batroxobin on correcting cerebral arterial, venous, and peripheral vascular diseases, to explore the mechanism of batroxobin on anti-thrombosis process.
The BE COOL Treatments (Batroxobin, oxygEn, Conditioning, and …
网页2022年10月20日 · Batroxobin could be an effective adjunctive therapy to traditional anti-coagulation and anti-platelet treatments due to its proven safety and low incidence of hemorrhage transformation in multiple preliminary clinical studies [14,19,20,24,25].
Effects of batroxobin on the antithrombotic system in patients …
网页2024年8月4日 · Batroxobin, a thrombin-like serine protease extracted from Bothrops atrox moojeni venom, has been shown to exert defibrinogenating effects by releasing fibrinopeptide-A from fibrinogen and generating water-soluble fibrin monomers. 1 Moreover, batroxobin may induce endothelial cells to release tissue plasminogen activator (t …
Frontiers | Use of Batroxobin in Central and Peripheral Ischemic ...
网页2021年12月1日 · This review aims to summarize current study findings about batroxobin on correcting cerebral arterial, venous, and peripheral vascular diseases, to explore the mechanism of batroxobin on anti-thrombosis process.
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