Adefovir - Wikipedia
网页Adefovir dipivoxil. Adefovir works by blocking reverse transcriptase, an enzyme crucial for the HBV to reproduce in the body. It is approved for the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (primarily ALT) or histologically active ...
阿德福韦 - 百度百科
网页Adefovir dipivoxil为阿德福韦的口服制剂。 在治疗慢性乙肝时，其药量是治疗HIV感染的10%到25%，且毒副作用较小。 Xiong 等在体外实验中证实，对拉米夫定耐药的HBV仍阿德福韦敏感。
Adefovir dipivoxil - DrugBank Online
网页Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir. Type.
Adefovir Dipivoxil for the Treatment of Hepatitis B e …
网页2003年2月27日 · Adefovir dipivoxil (Hepsera, Gilead Sciences) is an oral prodrug of adefovir, an analogue of adenosine monophosphate. The active intracellular metabolite, adefovir diphosphate, inhibits HBV DNA...
Adefovir dipivoxil: a review of its use in chronic hepatitis B
网页Adefovir dipivoxil (Hepsera) is an oral prodrug of the nucleotide analogue adefovir. It is indicated for the treatment of chronic hepatitis B in adults. Adefovir dipivoxil 10 mg/day significantly improved histological, biochemical and virological outcomes in hepatitis B e antigen (HBeAg)-positive and -negative patients, and serological outcomes ...
Adefovir Dipivoxil: Package Insert - Drugs.com
网页2023年12月13日 · Adefovir dipivoxil tablets are a medicine used to treat people 12 years of age and older with chronic (long-lasting) infections with active hepatitis B virus. Adefovir dipivoxil tablets is not for use in children under 12 years of age. Adefovir dipivoxil tablets may lower the amount of hepatitis B virus (HBV) in your body.
adefovir dipivoxil, Hepsera (adefovir) dosing, indications ...
网页Medscape - Indication-specific dosing for adefovir dipivoxil, Hepsera (adefovir), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation...
Adefovir Dipivoxil for the Treatment of Hepatitis B e …
网页2003年2月27日 · Adefovir dipivoxil (Hepsera, Gilead Sciences) is an oral prodrug of adefovir, a phosphonate nucleotide analogue of AMP with potent activity against the polymerase activity of hepadnaviruses,...
Long-Term Therapy with Adefovir Dipivoxil for HBeAg-Negative Chronic ...
网页2005年6月30日 · Treatment with adefovir dipivoxil for 48 weeks resulted in histologic, virologic, and biochemical improvement in patients with hepatitis B e antigen (HBeAg)–negative chronic hepatitis B.
Adefovir DIPIVOXIL - Uses, Side Effects, and More - WebMD
网页Generic Name (S): adefovir. Uses. This medication is used to treat a chronic viral infection of the liver (hepatitis B). It works by slowing the growth of the virus, helping to lower the amount of...