Glycosyltransferases and Glycan-Processing Enzymes
网页Glycosyltransferases and glycosidases are responsible for the assembly, processing, and turnover of glycans. In addition, there are a number of transferases that modify glycans by the addition of acetyl, methyl, phosphate, sulfate, and other groups.
Glycosyltransferases: structures, functions, and mechanisms
网页Glycosyltransferases catalyze glycosidic bond formation using sugar donors containing a nucleoside phosphate or a lipid phosphate leaving group.
Glucosyltransferase - an overview | ScienceDirect Topics
网页Neuroscience. Glucosyltransferases are enzymes involved in the formation of various oligosaccharide structures in nature, similar to glycosidases. They can be classified as inverting or retaining based on their mechanism of action, and their structures belong to GT-A and GT-B folds.
Structure, function, and pathology of protein O-glucosyltransferases ...
网页2021年1月12日 · This systemic review comprehensively covers literature to understand the O -glucosyltransferases with a focus on POGLUT1 structure and function, and their role in health and diseases. Moreover ...
Structures and mechanisms of glycosyltransferases
网页2005年7月21日 · Glycosyltransferases (GTs) catalyze the transfer of a sugar moiety from an activated donor sugar onto saccharide and nonsaccharide acceptors. A sequence-based classification spreads GTs in many families thus reflecting the variety of molecules that can be used as acceptors.
UDP-glucosyltransferase regulates grain size and abiotic stress ...
网页2020年5月26日 · GSA1 encodes a UDP-glucosyltransferase, which exhibits glucosyltransferase activity toward flavonoids and monolignols. GSA1 regulates grain size by modulating cell proliferation and expansion,...
Glycosyltransferase structural biology and its role in the design of ...
网页2016年10月15日 · Glycosyltransferases (GTs) mediate the regio- and stereospecific transfer of sugars from various sugar donors to a variety of important biomolecules including glycans, lipids, peptides, and small molecules [ 1 – 3 ].
Emerging structural insights into glycosyltransferase-mediated ... - Nature
网页2019年8月19日 · Several recent crystal structures of glycosyltransferases with bound acceptor substrates reveal that these enzymes have common core structures that function as scaffolds upon which variable loops...
Structure, function, and pathology of protein O-glucosyltransferases
网页2021年1月12日 · The main players of protein O- glucosylation, protein O -glucosyltransferases (POGLUTs), use uridine diphosphate (UDP)-Glc as a substrate to modify EGF repeats and reside in the endoplasmic reticulum via …
Glucosyltransferase - an overview | ScienceDirect Topics
网页Glycosyltransferase catalyses the transfer of sugar moiety to flavonoid to generate flavonoid glycosides. According to the glycosyl donor preference, the glycosyltransferases are different. UDP glycosyltransferases, also called family 1 glycosyltransferases, are responsibile of catalysing the transfer of a glycosyl moiety in UDP sugar to flavonoid.
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