Podocyte - Wikipedia
网页Podocytes are cells in Bowman's capsule in the kidneys that wrap around capillaries of the glomerulus. Podocytes make up the epithelial lining of Bowman's capsule, the third layer through which filtration of blood takes place. [1]
足细胞 - 百度百科
网页足细胞呈星型多突状， 胞体 较大，由胞体伸出许多突起，又称 足突 （FP），呈指状交叉覆盖于 GBM 外表面，并通过 黏附分子 和蛋白多糖分子与GBM相连。. 扫描电镜 观察，可见胞体伸出几个大的初级足突，进而分出许多指状的次级突起。. 相邻两个足细胞之间的 ...
Podocytes - PMC - National Center for Biotechnology Information
网页2016年1月28日 · Regardless of the diverse origins of glomerular diseases, podocytes are critical determinants of outcome for all glomerular diseases, which makes podocytes a unique model for monitoring and investigating disease progression 355.
Podocytes - PubMed
网页2016年1月28日 · Podocytes are highly specialized cells of the kidney glomerulus that wrap around capillaries and that neighbor cells of the Bowman's capsule. When it comes to glomerular filtration, podocytes play an active role in preventing plasma proteins from entering the urinary ultrafiltrate by providing a bar ….
Cell Biology and Pathology of Podocytes - PMC - National Center …
网页Podocytes are pericyte-like cells with a complex cellular organization consisting of a cell body, major processes, and foot processes (FPs). Podocyte FPs elaborate into a characteristic interdigitating pattern with FPs of neighboring podocytes, forming in between the filtration slits that are bridged by the glomerular slit diaphragm (SD ...
New structural insights into podocyte biology - PMC
网页2017年3月10日 · Podocytes reside as specialized pericytes covering the glomerular capillary endothelial cells towards the parietal epithelial cells that coat Bowman’s capsule (Fig. 1a; Greka and Mundel 2012).
Podocyte-targeted therapies — progress and future directions
网页2024年5月9日 · Podocytes are the key target cells for injury across the spectrum of primary and secondary proteinuric kidney disorders, which account for up to 90% of cases of kidney failure worldwide.
Podocytes | Nature Reviews Nephrology
网页2024年5月9日 · This Review provides an overview of the role of the kidney in the synthesis, degradation, filtration, reabsorption and excretion of different amino acids and the relevance of these functions in ...
Editorial: Molecular and Cellular Biology of podocytes
网页2022年10月9日 · Podocytes are highly differentiated (post-mitotic) epithelial cells that are attached to the glomerular basement membrane. They are an essential part of the filtration barrier, preventing the loss of serum proteins into the urine.
Role of biophysics and mechanobiology in podocyte physiology
网页2024年3月5日 · Throughout the past two decades, a holistic picture of podocyte cell biology has emerged, highlighting mechanobiological signalling pathways, cytoskeletal dynamics and cellular adhesion as key ...