Pralidoxime - Wikipedia
网页Pralidoxime (2-pyridine aldoxime methyl chloride) or 2-PAM, usually as the chloride or iodide salts, belongs to a family of compounds called oximes that bind to organophosphate-inactivated acetylcholinesterase. [1] It is used to treat organophosphate poisoning [2] in conjunction with atropine and either diazepam or midazolam. It is a white solid.
Pralidoxime Uses, Side Effects & Warnings - Drugs.com
网页2024年6月18日 · Pralidoxime is used as an antidote to treat poisoning caused by chemicals, pesticides (insect sprays), or drugs used to treat a muscle disorder. This medication is not effective as an antidote for all types of pesticide poisonings.
Pralidoxime - StatPearls - NCBI Bookshelf
网页2023年5月1日 · Pralidoxime is a medication used in the management and treatment of organophosphate poisoning. It is in the oxime class of drugs. This activity outlines the indications, action, and administration of pralidoxime therapy as a valuable agent in managing the toxicity of organophosphate-based pesticides and nerve agents.
Pralidoxime: Uses, Interactions, Mechanism of Action - DrugBank …
网页2005年6月13日 · Pralidoxime is a cholinesterase reactivator used to treat organophosphate poisoning. Pralidoxime is an antidote to organophosphate pesticides and chemicals. Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme.
Pralidoxime: Side Effects, Uses, Dosage, Interactions, Warnings - RxList
网页Pralidoxime is an antidote used for reversing organophosphate poisoning and acetylcholinesterase inhibitor toxicity (Neostigmine, Pyridostigmine). Learn about side effects, dosages, drug interactions, and more.
Pralidoxime Chloride: Package Insert - Drugs.com
网页2024年3月25日 · Pralidoxime chloride is a cholinesterase reactivator. The principal action of pralidoxime is to reactivate cholinesterase (mainly outside of the central nervous system) which has been inactivated by phosphorylation due to an organophosphate pesticide or related compound.
Pralidoxime: Antidote Uses, Side Effects, Dosage - MedicineNet
网页2024年1月18日 · Pralidoxime is a medication used as an antidote to treat poisoning due to certain types of organophosphate pesticides and nerve agents. Pralidoxime is also used to reverse the effects of certain drugs used in treating myasthenia gravis.
Pralidoxime Monograph for Professionals - Drugs.com
网页2024年5月10日 · Introduction. Cholinesterase reactivator; quaternary ammonium oxime. Uses for Pralidoxime. Pesticide Poisoning. Concomitantly with atropine to reverse muscle paralysis (particularly of respiratory muscles) associated with toxic exposure to organophosphate anticholinesterase pesticides.
Pralidoxime: Dosage, Mechanism/Onset of Action, Half-Life
网页2020年2月10日 · Includes Pralidoxime indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more.
Protopam, 2PAM Antidote (pralidoxime) dosing, indications, …
网页Medscape - Indication-specific dosing for Protopam, 2PAM Antidote (pralidoxime), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules,...