Vertical Transplacental Infections - StatPearls - NCBI Bookshelf
网页2024年8月16日 · Viral transplacental infections represent a critical category of maternal-fetal health concerns, with the capacity to traverse the placental barrier and adversely affect the developing fetus, leading to a range of outcomes, from mild disease to severe congenital anomalies or fetal death.
Benefits and Risks of IgG Transplacental Transfer - PMC
网页2020年8月12日 · The transplacental transfer of IgG platelet-specific autoantibodies can induce fetal platelet destruction and cause neonatal thrombocytopenia. The majority of infants born to mothers with ITP may have normal or mild thrombocytopenia, but the full count may decrease sharply in two to five days after birth [ 88 ].
Transplacental transmission of the COVID-19 vaccine messenger …
网页2024年1月31日 · The initial clinical trials for the COVID-19 messenger RNA (mRNA) vaccines excluded pregnant women, leading to a knowledge gap concerning the potential biodistribution of the vaccine’s mRNA to the placenta and/or the fetus after maternal vaccination. The Pfizer and Moderna Assessment Reports that were provided to the European Medicines Agency ...
Transplacental transmission of SARS-CoV-2 infection - Nature
网页2020年7月14日 · We demonstrate the transplacental transmission of SARS-CoV-2 in a neonate born to a mother infected in the last trimester and presenting with neurological compromise.
SARS-CoV-2 Transplacental Transmission: A Rare Occurrence? An …
网页2023年2月25日 · Plausible SARS-CoV-2 transplacental infective mechanisms and the various placental defense to prevent mother-to-fetal transmission. Abbreviations: ACE2: angiotensin converting enzyme 2; C19MC: chromosome 19 microRNA cluster; CTSL: cathepsin-L; DPP4: dipeptidylpeptidase-4; miRNAs: microRNAs; NK: natural killer; TMPRSS2: transmembrane serine ...
Maternal immune response and placental antibody transfer after
网页2022年6月28日 · Higher transplacental transfer ratios following first and second trimester vaccination may reflect placental compensation for waning maternal titers. These results provide novel insight into the...
Evaluation of transplacental transfer of mRNA vaccine products …
网页2022年7月30日 · We examined the transplacental transfer of mRNA vaccine products and humoral responses using samples from pregnant individuals and their infants vaccinated with either BNT-162b2 or mRNA-1273 mRNA...
SARS-CoV-2 Transplacental Transmission: A Rare Occurrence? An …
网页2023年2月25日 · A better understanding of the placental barrier, immune defense, and modulation strategies involved in restricting transplacental transmission may provide valuable insights for future development of antiviral and immunomodulatory therapies to improve pregnancy outcomes.
Transplacental Definition & Meaning - Merriam-Webster
网页The meaning of TRANSPLACENTAL is passing through or occurring by way of the placenta. How to use transplacental in a sentence.
Placental Transfer - an overview | ScienceDirect Topics
网页The placenta regulates maternal-fetal molecular and fluid exchange. Transplacental transfer of molecules may occur via extracellular or transcellular routes.
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