na. | 1. Disease has spread to the vital organs -- regarded as hopeless.; be at death's door from one's illness; be a wreck and rotten to the core; be incurably sick; be past treatment; catch one's death of a cold; fatal disease; be mortally [critically] ill; beyond all hope; beyond remedy; have no hope of recovery; The disease has attacked one's very vitals -- beyond cure.; The illness has taken deep root in one's lean (and weak) body.; The illness is now deeply rooted in one's system. |