TP53

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1.
Polymorphisms in the TP53 locus that might have cancer-related phenotypical manifestations are the subject of this Review.
多态性TP53基因可能与癌症有关的表型表现的主题的本次审查。
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2.
No associations were found between any of the clinical or pathological features of hereditary breast cancer with somatic TP53 mutations.
遗传性乳腺癌任何临床或病理特征与体细胞TP53突变无关。
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3.
One of the most frequently mutated genes in human cancers, tumour suppressor p53 (TP53), can induce cell-cycle arrest and apoptosis.
其中最常见的基因突变在人类癌症，肿瘤抑制p53蛋白（TP53），可诱导细胞周期阻滞和凋亡。
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4.
We evaluated TP53 mutations and survival in patients with squamous-cell carcinoma of the head and neck.
我们评估了TP53突变与头颈部鳞状细胞癌患者存活率的关系。
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5.
The TP53 tumor suppressor gene is involved in a multiple cellular processes.
TP53肿瘤抑制基因参与了多种细胞内过程。
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6.
TP53 is probably the most extensively studied tumour-suppressor gene, and patients with TP53 mutations are known to have a poor outcome.
tp53的可能是最广泛研究的肿瘤抑制基因，并与tp53的突变的患者已知有一个贫穷的结果。
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7.
TP53 mutational status was compared with clinical outcome.
同时比较了TP53突变状况与临床结果的关系。
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8.
For example, mutations in RUNX1, TP53, and NRAS were associated with severe thrombocytopenia and blast percentage.
如RUNX1、TP53、NRAS中的突变与重度血小板减少症及原始细胞比例相关。
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