No biological system has been studied by more diverse approaches than the actin-based molecular motor myosin. Biophysics, biochemistry, physiology, classical genetics and molecular genetics have ...

Muscle fibers in children with SMA type 1 show substantial differences in components of the myosin protein called heavy ...

UConn physiologist and geneticist Jianjun Sun, a professor in the Department of Physiology and Neurobiology, suspected that ...

An individual sarcomere contains many parallel actin (thin) and myosin (thick) filaments. The interaction of myosin and actin proteins is at the core of our current understanding of sarcomere ...