Aldosterone is a hormone produced in the adrenal ... levels of potassium in the blood through many mechanisms, including action on the mineralocorticoid receptors in the kidneys.

However, this contributes to the pathology of the disease by, among other actions, increasing the release of aldosterone. Aldosterone has been shown to cause coronary inflammation, cardiac ...

Both insulin resistance and obesity have substantial effects on aldosterone action; 7,8 hence, the prevalence of these conditions in a study population might influence the clinical response to ...

It is unclear whether these beneficial effects are due solely to aldosterone blockade, as MR has a similar affinity for cortisol. We examined the relationships between plasma and urinary steroid ...