Eplerenone, a specific aldosterone receptor blocker with a lower incidence of the sex hormone-related side effects than spironolactone, has been used in several recent clinical trials in ...

Eplerenone is a new aldosterone receptor antagonist that will be used in the treatment of hypertension. Like spironolactone, it is a compound that can be associated with the development of ...

The trial aims to determine the effects of aldosterone receptor antagonism on mortality and cardiovascular outcomes (onset or progression of cardiovascular disease) in patients with stage 3b CKD ...

Aldosterone is a hormone produced in the adrenal ... including action on the mineralocorticoid receptors in the kidneys. It plays a central role in the regulation of blood pressure.