Hematopoietic stem cells (HSCs) are the precursors of all cells of the peripheral blood, and they usually reside in a quiescent state in the bone marrow. We discovered that interferon gamma (IFNγ) ...

After bone marrow transplantation ... occurs through cell fusion of hepatocytes with HSC progeny cells, most likely macrophages. Shown are the differentiation of hematopoietic cells to myeloid ...

Bone marrow-derived epithelial cells arise by cell fusion, not differentiation, and oval cells are generated from intrahepatic stem cells, not bone marrow precursors. Cell types that originate ...

If we can understand how stem cells are maintained, we could potentially expand HSC ex vivo allowing improved bone marrow transplantation and cancer treatments ... In mouse embryonic stem (ES) cells, ...

We are interested in the development of B lymphocytes and their subsequent antigen-dependent differentiation into effector cells ... and severe immunosuppressive regimens involved in a variety of ...

Bone marrow is a soft, spongy material inside your bones where blood cells are made. These blood cells are important for a healthy immune system. (Photo Credit: Wendy Hiller Gee/Eric Olson/WebMD ...

Since cases of radiation disaster may occur, and since bone-marrow deficiency from radiation or chemotherapy does occur in the normal course of clinical medicine, an effort has been made to ...

For example bone marrow stem cells only form different ... This process is called cell differentiation. A small bundle of cells made from embryonic stem cells is called an embryo.

A stem cell transplant can be a good treatment for multiple myeloma. A successful transplant gives someone with multiple myeloma new, healthy bone marrow. It replaces the bone marrow harmed by myeloma ...