In rat adjuvant-induced arthritis (AIA), CCL5 levels peak before disease onset but CCL2 levels only rise once joint inflammation is fully established. Outcomes of CCL2 or CCL5 blockade are thought ...
Dominant induction of HIV-1-specific cell-mediated immunity [127] pDNA (CCL5, CXCL13, CCL2) + pDNA (gp120) + pDNA (gp160) – Influence the outcome of immune responses according to their predicted ...
CSF samples from all patients were analyzed using bead flow cytometry to detect levels of cytokines (IL-2, IL-4, IL-6, IL-10, TNF and IFNγ) and chemokines (CCL2, CCL5, CXCL8, CXCL9, and CXCL10).
MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...
CCL2和CCL5通过反馈招募巨噬细胞并增强破骨细胞分化。这些作用有助于肿瘤细胞骨组织的定植,休眠肿瘤细胞重新激活,以及溶骨性骨转移的进展。