New research from the laboratory of Bruce Spiegelman (now based at the Dana–Farber Cancer Institute, Boston, USA), which discovered PPARγ in 1987, provides some clues as to how and why this ...

A high density of tumor-associated macrophages (TAMs) is associated with poorer prognosis and survival in breast cancer patients. Recent studies have shown that lipid accumulation in TAMs can promote ...

Highly potent but poorly water-soluble drug (PWSD) candidates are common outcomes of contemporary drug discovery programmes. These lipophilic compounds often exhibit poor systemic exposure ...

PPARs are categorized into three subtypes: PPARα, PPARβ/δ, and PPARγ. Each subtype plays distinct roles in cancer development and progression, with their activation or inhibition leading to ...

PPARs are categorized into three subtypes: PPARα, PPARβ/δ, and PPARγ. Each subtype plays distinct roles in cancer development and progression, with their activation or inhibition leading to ...

Everything we can see and touch, and quite a lot that we can’t as well, is made of tiny particles called atoms. Some substances, like particles of this iron, contain only one kind of atom.

The pH scale shows how acidic a substance is. Learn what pH means and how it is measured in this KS3 chemistry guide from BBC Bitesize. Neutralisation reactions Acids and alkalis react together in ...

A colon is used to give emphasis, present dialogue, introduce lists or text, and clarify composition titles. Emphasis—Capitalize the first word after the colon only if it is a proper noun or the start ...

Two contestants pit their linguistic and numerical skills against each other and the clock in this entertaining quiz show. Two contestants pit their linguistic and numerical skills against each ...

Y&R’s Melody Thomas Scott Promises Nikki’s Nightmare Isn’t Over Jan 11, 2024 The Young and the Restless Y&R’s Lauralee Bell, Michael Damian, and Michelle Stafford Are Back at it Again! Oct ...

Music-driven comedy caper. Andy and the Band risk missing their next gig by taking on super-weird Odd Jobs for their fans. A madcap mix of songs, slapstick and silliness. ABC iview Home Watch all your ...