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腾讯网
14 天
【Cell子刊】清华大学林欣团队:揭示TCR-STAR超越CAR-T,精准狙击低 ...
【导读】针对肿瘤特异性新抗原的免疫治疗具有潜力,但它们在肿瘤细胞上的超低表达,对T细胞治疗提出了挑战。在这项研究中,团队发现,嵌合抗原受体(CARs)在针对人类白细胞抗原(HLA)I类呈现的p53R175H新抗原时,其敏感性比T细胞受体(TCRs)低 ...
News Medical on MSN
27 天
Intrinsic factors of the CAR-T cells may play a major role on its clinical success
Researchers from the Josep Carreras Leukaemia Research Institute have found that the efficacy of varni-cel, a CAR-T infusion ...
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