However, recent studies have indicated new roles for centrosomes in cytokinesis and cell-cycle progression. Is it possible that a common 'thread' connects all three sets of findings? Careful ...

Each centrosome pushes the chromosome from each side until they ... Telophase: Have students compare the progression through the cell cycle up to this point. Have them identify patterns in how the ...

Moreover, the ordered events of the cell cycle (DNA replication, centrosome duplication, spindle assembly and chromosome segregation) were cases in which early events provided the substrates for ...

Many cancer cells, for example, exhibit abnormal chromosome numbers and extra centrosome. Typically, before such defective ...

The goal of my research is to understand the biogenesis of centrioles/centrosomes and primary cilia, and how defects in these processes affect mammalian cell physiology and evoke stress responses.

Many cancer cells, for example, exhibit abnormal chromosome numbers and extra centrosome. Typically, before such defective cells can survive and grow, they arrest their cell cycle, or trigger ...