Errors in these checkpoints can have catastrophic consequences, including cell death or the unrestrained growth that is cancer. Another important checkpoint takes place later in the cell cycle ...

Abatacept reduces immune activity by enhancing the activity of CTLA-4, a checkpoint receptor that tamps down T cell activation. By turning off immune responses through this mechanism, Abatacept ...

Programmed cell death-1, or PD-1, has become a headline-grabbing molecule best known for its role in cancer immunotherapies called checkpoint inhibitors. A study from Georgia Tech and Emory ...

Researchers at the University of Michigan Rogel Cancer Center have discovered a key reason why some cancers do not respond to ...

A video posted on social media on Thursday reportedly showed moments when a young Palestinian woman was shot to death by ... military checkpoint. The video, filmed on a cell phone by a bystander ...