Scientists Are Teaching Cells to Record Their Own Histories
The engineered cells could help researchers understand how cells work together and trace the origins of certain illnesses ...
Cell model identifies important factor in neural development
The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine ...
生物谷8 天
Cell：新型条形码技术Patho-DBiT有望更精确地诊断癌症
Patho-DBiT利用DNA条形码绘制RNA和蛋白的空间关系图，对RNA（某些类型的RNA在癌症中具有调控作用）进行全面探究。这项技术的独特之处在于，它拥有微流体设备，能从两个方向将条形码送入组织，形成独特的二维像素“马赛克”，提供空间信息，从而可 ...
eLife13 天
Introduction of cytosine-5 DNA methylation sensitizes cells to oxidative damage
This important work advances our understanding of DNA methylation and its consequences for susceptibility to DNA damage. This work presents evidence that DNA methylation can accentuate the genomic ...
GEN1 天
Rare Genetic Disorder Helps Explain Link Between Cancer Immunotherapy and Increased Infections
Studying patients with PD-1 or PD-L1 deficiency may help inform new approaches to fine-tuning immunotherapies to maximise ...
Science Daily7 天
DNA repair: A look inside the cell's 'repair café'
New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...