For almost a century, our understanding of the tiny structure at the centre of the cell called the centrosome was limited to its ability to organize mitotic spindles and other microtubule arrays.
The centrosome has been a subject of fascination for cell biologists for at least a century. It is at the centre of the cell and is the structure on which microtubules organize themselves both ...
The goal of my research is to understand the biogenesis of centrioles/centrosomes and primary cilia, and how defects in these processes affect mammalian cell physiology and evoke stress responses.