Earnshaw and Naomi Rothfield reported that antibodies from the sera of patients with scleroderma, an autoimmune disease, reacted with centromeres. They named the proteins that reacted with these ...
Researchers from the Max Planck Institute have elucidated the molecular mechanism regulating the replenishment of centromeric protein A (CENP-A) at the centromere. The study reveals how Polo-like ...
At the heart of the kinetochore is a specialized nucleosome that contains centromere protein (CENP)-A, a histone H3 homologue. Several inner kinetochore components (cyan and purple ovals ...