Earnshaw and Naomi Rothfield reported that antibodies from the sera of patients with scleroderma, an autoimmune disease, reacted with centromeres. They named the proteins that reacted with these ...

These CENP-A proteins ensure that divided genetic information is kept intact during mitosis.

Enzyme: This game-changing protein might be the key to understanding how our cells divide and why cancer happens. Here's what ...

Researchers from the Max Planck Institute have elucidated the molecular mechanism regulating the replenishment of centromeric protein A (CENP-A) at the centromere. The study reveals how Polo-like ...

The cell division machinery identifies centromeres by the presence of multiple copies of a protein known as CENP-A. But every ...

Centromeres coordinate the precise ... of PLK-1 in this reaction (including work by the same team on one of the proteins that PLK-1 is phosphorylating), but scientists did not understand the ...

At the heart of the kinetochore is a specialized nucleosome that contains centromere protein (CENP)-A, a histone H3 homologue. Several inner kinetochore components (cyan and purple ovals ...

This project began with a puzzling observation. A protein called CENP-A marks the centromere at all times, and forms the very ...