The lack of centrioles could therefore prevent cytokinesis in all acentrosomal cell systems examined. Figure 1: Positioning of centrosomes and spindle pole bodies during exit from cytokinesis.

The two centrioles together with their associated pericentriolar material constitute the ‘centrosome’. In motile animal cells, such as fibroblasts or macrophages, the centrosome typically ...

As the centrioles move toward the poles of the cell, they create a region of cytoskeletal production called the centrosome. Be mindful of the vocabulary you introduce to your students. The long ...

The goal of my research is to understand the biogenesis of centrioles/centrosomes and primary cilia, and how defects in these processes affect mammalian cell physiology and evoke stress responses.