Patients with confirmed tophi and more frequent acute gout attacks ... patients who reported symptoms of inadequately controlled chronic gout (similar to refractory chronic gout), defined here ...

and chronic gouty arthritis with multiple gouty tophi. He had also had hyperuricemia for many years, with uric acid concentrations of up to 9.8 mg/dl. Initial treatment with febuxostat 80 mg bid ...

and chronic gouty arthritis with multiple gouty tophi. He had also had hyperuricemia for many years, with uric acid concentrations of up to 9.8 mg/dl. Initial treatment with febuxostat 80 mg bid ...

Gout tophi totally disappeared and renal function ... It can present as acute synovitis (pseudo gout attack) or chronic arthropathy; more often than not it is asymptomatic COMPENSATED POLARIZED ...

In some individuals, particularly the elderly, gout episodes become chronic, and crystals of uric acid metabolism byproducts are deposited over the affected joint, forming swellings known as tophi.