It is unclear whether these beneficial effects are due solely to aldosterone blockade, as MR has a similar affinity for cortisol. We examined the relationships between plasma and urinary steroid ...
Both cortisol and aldosterone are potent activators of renal MCRs. In vitro, cortisol is a tenfold more potent activator of the MCR than aldosterone. In the kidney, 11β-hydroxysteroid ...
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