Cyclosporine (modified) 100mg/mL; contains alcohol. Give consistently with regard to meals and time of day. ≥18yrs: 1.25mg/kg twice daily; may increase by 0.5–0.75mg/kg per day after 8 weeks ...
Data on patient demographics, cyclosporine dosages, dosage form, blood trough concentrations, clinical laboratory test values, and concurrent medications were collected. One-compartment models for ...
From the current literature, it seems unlikely that modified absorption or altered CYP3A4 metabolic activity contributed to the observed decrease in cyclosporine clearance when the drug was ...