底部为两个GEL患者的FISH（荧光原位杂交）图像和AmpliconArchitect结构变异视图。左侧的例子展示了与FISH图像一致的染色体扩增，而右侧的例子则展示了与FISH图像一致的染色体外DNA（ecDNA）。

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POLK expression in neurons and report an important observation that POLK exhibits an age-dependent change in subcellular localization, from the nucleus in young tissue to the cytoplasm in old tissue.