It created the first map of DNA modification in the hippocampus and prefrontal cortex -; two regions of the brain critical to learning, memory and emotional regulation. These areas are also ...
Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence ...
A team of researchers has successfully used DNA as a data storage medium, with a method inspired by old printing techniques. The idea isn't new: DNA, capable of storing immense amounts of ...
DNA can last for many centuries. A new DNA storage technology works in the laboratory with parallelizable writing processes ...
The scientists created an algorithm that reconstructs the epigenetic landscape of ancient brains—chemical modifications to ...
But DNA has an added layer of information encoded on top of the nucleotide sequence, known as epigenetics. These are chemical modifications to the nucleotides, specifically altering a C when it ...
Other cytosine modifications include: 5-Hydroxymethylcytosine (5hmC): An oxidized form of 5mC that is involved in DNA demethylation and gene regulation. 5-Formylcytosine (5fC) and 5-Carboxylcytosine ...
“Every cell in our bodies has the same genome sequence, but genetic programming comes from modifications to DNA. If life can do this, we can do this,” she says. Qian and her colleagues ...
Histone modification can also attract DNA methyltransferases to initiate cytosine methylation, which in turn can reinforce histone modification patterns conducive to silencing. Experiments in ...
Histones not only keep DNA organized, but also help regulate gene expression. How? Scientists are using ChIP and PCR to find out. To examine changes in histone modification during blood cell ...