LTβR –induced non-canonical NFκB activation in various stromal subsets within the SLOs is obligatory for the full differentiation of marginal reticular cells (MRC), follicular dendritic cells ...

Plasmacytoid dendritic cells (pDCs) are a unique subset of immune cells originating from the bone marrow, playing a crucial ...

Some patients being treated with immune checkpoint inhibitors, a type of cancer immunotherapy, develop a dangerous form of heart inflammation called myocarditis. Researchers have now uncovered the ...

This manuscript introduces DendroTweaks, a useful web application and Python library that, compared to existing modeling tools, eases interactive graphical exploration, development, and validation of ...

Some patients being treated with immune checkpoint inhibitors, a type of cancer immunotherapy, develop a dangerous form of heart inflammation called myocarditis. Researchers led by ...

Figure 1: The crucial role of dendritic cells ... for therapy because they not only target tumour cells but also pro-angiogenic stromal components. Treatment with granulocyte-macrophage colony ...

What are germ cell and sex cord stromal cells? Germ cells and sex cord stromal cells form when a fetus (baby) is developing. A fetus is made from a sperm cell and an egg cell. Germ cell tumors (GCTs) ...

at the Max Planck Institute of Molecular Physiology identified a chemical substance that proved to be highly effective against drug-resistant gastrointestinal stromal tumor cells in preclinical ...

According to many experts, we may soon find ourselves using fuel cells to generate electrical power for all sorts of objects we use every day. A fuel cell is a device that uses a source of fuel ...

During pregnancy, the maternal immune system must engage in a fine balancing act: maintaining tolerance to the fetal allograft while restoring innate and adaptive immune mechanisms for protection ...

Cells are the smallest unit of life and the building blocks for all organisms. Each component of a cell has its own function. Animal and plant cells differ and they have similarities. Nucleus ...