The present study quantifies the impact of the presence of tophi and frequency of acute gout attacks on health-related quality of life (HRQOL), productivity, and healthcare resource utilization.

Patients with tophi also had significantly greater impairment of work productivity and activity. Tophaceous gout was associated with greater absenteeism and overall work impairment than both the ...

Tophaceous gout is a severe form of gout. It results when uric acid crystals form, leading to growths called tophi around the ...

and chronic gouty arthritis with multiple gouty tophi. He had also had hyperuricemia for many years, with uric acid concentrations of up to 9.8 mg/dl. Initial treatment with febuxostat 80 mg bid ...