Valeant and Progenics’ Relistor (methylnatrexone) opioid-induced constipation drug has been approved in pill form, potentially giving the companies a blockbuster gastrointestinal drug.

The financial burden of chronic constipation is considerable, due to direct costs of the healthcare system such as consultations, investigations, and drug therapy. [9] Constipation is often ...

Mounjaro is a prescription drug, and like most drugs it can cause side effects, such as constipation. Over-the-counter laxatives and lifestyle changes may help relieve constipation. Digestive side ...

Medicines can cause constipation. Opioids are probably the most commonly known cause of drug-induced constipation, but there ...

Opioids are often first-line treatments for cancer-related pain, but they can suppress the immune system and reduce the ...

Other exclusion criteria were: drug-induced constipation; central or peripheral neurological abnormalities; metabolic and endocrine disorders (diabetes mellitus, porphyria, hypothyroidism ...

The deal is essentially a move to take control of Movantik (naloxegol), which is indicated for the treatment of one of the most prominent side effects of opioid analgesics – constipation – in ...