Fanconi anemia (FA) is a rare genetic disease, affecting 1 in 160,000 people. The condition leads to gradual bone marrow failure in about 90% of people affected. Bone marrow is the spongy material ...

Although rare, Fanconi anaemia is the most common form of inherited bone marrow failure that requires bone marrow transplantation therapy in Saudi Arabia. Paediatrician Abdulrahman Alsultan and ...

The genetic basis of Fanconi anemia (FA) is mysterious and complex, as none of the five genes previously associated with the disorder have homology to genes encoding proteins of known function.

The Fanconi Anemia pathway, named after a cancer-predisposition syndrome, is essential for the repair of DNA-interstrand crosslinks (ICLs). The pathway consists of 22 FA complementation group proteins ...

The community unites to host a music festival to fundraise for Dylan René, 6, and her father, Josiah Menard who are facing ...

Their hunt narrowed to a set of genes involved in the Fanconi anemia pathway—a DNA repair mechanism mutated in an eponymous germline condition marked by severe anemia, bone marrow failure ...

Using data from the Kidz1stFund Comprehensive Fanconi Anemia Center led by Margaret MacMillan, MD, and John Wagner, MD, ...

What are the Common Causes of Anemia in CHF ... reduced activity of EPO in the bone marrow, hepcidin-induced failure of iron absorption from the gut, and hepcidin-induced trapping of iron in ...

New Delhi: The Central government is set to launch a scheme to develop 12 indigenous drugs for eight rare diseases, health ...

Bone marrow transplant for aplastic anemia Aplastic anemia is a rare disease that causes your bone marrow to stop producing blood cells, making it a very serious illness. A blood transfusion can ...

Its clinical program is an LVV-based gene therapy for the treatment of Fanconi Anemia (FA), a difficult to treat genetic disease that leads to bone marrow failure and potentially cancer.

How Does Anemia Worsen CHF? The question of how anemia worsens CHF was recently reviewed. [37] Anemia causes a fall in systemic vascular resistance, attributable, in part, to the reduced viscosity ...