引言癌症是当今世界上最具挑战性的健康问题之一,尤其是肺癌,作为致死率最高的癌症类型,每年夺走数百万人的生命。随着研究人员对癌症的深入研究,人们逐渐认识到,癌症不仅仅是恶性细胞的过度增殖,更是一种与“宿主”复杂相互作用的生态系统。肿瘤微环境(Tumor ...
and fibroblastic reticular cells (FRC). Conversely, stromal cell-derived chemokines such as CXCL13 govern the positioning of T and B cells, establishing SLO structures with segregated zones ...
Aldh1a2+ fibroblastic reticular cell (FRC)-derived retinoic acid induces CXCL12 expression in the endothelium, which regulates the constitutive recruitment of circulating lymphocytes to the milky ...