Study: Human PERIOD3 variants lead to winter depression-like behaviours via glucocorticoid signalling ... in monoamine ...

New research has unveiled how gut bacteria play a key role in regulating stress by interacting with circadian rhythms, ...

In vertebrates, an important mechanism for coping with stressors begins with adrenally-derived glucocorticoid hormones: corticosterone in amphibians, reptiles, and birds, or cortisol in fish and ...

Mechanism of Action Glucocorticoid-induced osteoporosis (GIO) is the second most prevalent cause of osteoporosis after postmenopausal estrogen deficiency. Glucocorticoids have both direct and ...

A pioneering study has uncovered the vital role that gut microbiota plays in regulating stress responses by interacting with ...

The activation of FLT3 promotes the proliferation mechanisms of the cell, a hallmark of cancer, one of which is the inactivation of the glucocorticoid receptor, rendering the cell insensitive to ...

New research links gut microbes to stress regulation, revealing their role in managing circadian rhythms and influencing ...

Examination of the airways in steroid-resistant asthmatic patients suggests that there is more than one mechanism for the lack of response to glucocorticoid therapy. Wenzel and associates [4 ...

Epidural glucocorticoid injection is an intervention commonly used for managing lumbosacral radicular pain. The goal of the injection is to administer glucocorticoids to the epidural space to ...

New research from reveals that the gut microbiome regulates the body's diurnal (day-night) rhythms in stress hormones. Depletion of gut microbiota results in disruptions in the brain's core circadian ...