Selenium-containing glutathione peroxidase (GPX) Protects cells from hydrogen peroxides and lipid hydroperoxides. If not neutralized, these peroxides will damage cellular membranes and other vital ...
Among these, the selenoenzyme glutathione peroxidase 4 (GPX4) stands out, playing a key role in preventing ferroptosis by protecting cells against damaging (phospho)lipid peroxidation. The team ...
J Biol Chem. 2005 Mar 25;280(12):11829-39. Epub 2005 Jan 10. Brenot A, King KY, Janowiak B, Griffith O, Caparon MG., Contribution of glutathione peroxidase to the virulence of Streptococcus pyogenes.
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