Researchers have identified a new complex-carbohydrate biomolecule, or glycan, that plays a key role in the nasal colonization of the Bordetella bacteria responsible for whooping cough. The discovery ...

glycan-masked eOD-GT8 60mer mutants may serve as improved priming immunogens to elicit VRC01-class bnAbs in humans. • HIV-1 vaccine- the priming component in a prime-boost approach.

First, the vaccine glycan coat binds to lectins, providing a primary signal. Then, binding to toll-like receptors elicits ...

By dissecting the role of mucin's protein and glycan components, researchers reveal the complex interactions between diet and gut bacteria, offering insights for future therapeutic applications.